Fear Conditioning

The Pavlovian Fear Conditioning task allows for the assessment of learning and memory regarding aversive events. The task allows for the simultaneous assessment of learning about simple, unimodal cues and learning about complex, multimodal stimuli such as context. Fear conditioning universally depends on the integrity of the amygdala, but context conditioning is sensitive to manipulations of the hippocampus. This task takes advantage of the rodent's natural defense of freezing (lack of motion) as a good indicator of fear level. This task has been used extensively to demonstrate both genetically based impairments and enhancements in learning and memory.

Procedure

After training in Context A, subjects level of freezing behavior is recorded after a retention delay.

Contextual Conditioning

In a contextual conditioning experiment, subjects are returned to Context A where their freezing is measure in response to the conglomerate of complex contextual stimuli.

Cued Conditioning

In a cued conditioning experiment, subjects are are placed in a novel context, and freezing behavior is examined with and without a fear-associated cue.

Behavioral Tasks


Fear Conditioning

Rat Services
Fear Conditioning
Startle/PPI
Morris Water Maze
Radial Arm Maze
T Maze
Social Interaction
Ultrasonic Vocalization
Conditioned Taste Aversion
Conditioned Place Preference
Novel Object Recognition
Aggression
Open Field
Roto-Rod
SHIRPA Primary Screen
Elevated Plus Maze
Light-Dark Box
Social Recognition
Social Transmission
of Food Preference
Basic Neurological Screens
° Vision Penlight
° Hot Plate
° Tail Immersion
° Grip Strength
° Gait Analysis
° Balance Beam
° Forced Swim
° Tail Suspension

AND many more
available tests...

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